Description

N Nitroso Sertraline is a specialized organic compound of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and analytical profiling of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, analytical laboratories, and pharmaceutical manufacturers engaged in advanced chemical synthesis, impurity identification, and method development. The material is handled under controlled conditions to maintain its integrity for precise scientific applications.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthetic pathways for novel therapeutic agents.
• Analytical Reference Standard: Used for method development, validation, and quantification in HPLC, LC-MS, and GC-MS analyses.
• Impurity Profiling and Identification: Serves as a certified reference material (CRM) to identify and control nitrosamine impurities in active pharmaceutical ingredients (APIs), ensuring compliance with stringent regulatory guidelines.
• Process Chemistry & Scale-Up: Employed in optimizing manufacturing processes during the development and scale-up of pharmaceutical compounds.
• Metabolite Studies: Used in pharmacological and toxicological research to study drug metabolism pathways.
• Quality Control & Assurance: Essential for in-house quality control laboratories to establish specification limits and ensure batch-to-batch consistency.

Basic Information

Product Name	N Nitroso Sertraline
CAS No.	3006789-98-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sertraline N-Nitroso Derivative; N-Nitrososertraline; (1S,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine N-nitroso; Nitrosamine Impurity of Sertraline; Sertraline Nitrosamine; Sertraline Related Compound NNO
EINECS	Contact for details

Quality Control

Our N Nitroso Sertraline is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high standards required for research and analytical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0% Total impurities ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.