Description

Pasireotide is a synthetic cyclic hexapeptide and a potent somatostatin analog with high affinity for multiple somatostatin receptor subtypes. This compound is a critical active pharmaceutical ingredient (API) valued for its targeted therapeutic action in managing hormone-secreting tumors. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of advanced endocrine disorder treatments.

Application

• Pharmaceutical API: Core active ingredient in the manufacture of injectable therapeutics for acromegaly and Cushing's disease.
• Oncological Research: Used in preclinical and clinical studies targeting neuroendocrine tumors (NETs) due to its antiproliferative effects.
• Endocrinology Studies: A key tool for investigating the somatostatin signaling pathway and developing novel hormone modulation therapies.
• Drug Formulation Development: Serves as a reference standard and a key component in the development of sustained-release formulations and drug delivery systems.
• Biochemical Research: Employed in receptor binding assays and pharmacological studies to understand peptide-receptor interactions.

Basic Information

Product Name	Pasireotide
CAS No.	396091-73-9
Molecular Formula	C58H66N10O9
Molecular Weight	1055.2 g/mol
Synonyms	Pasireotide; SOM230; Cyclo[(4R)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-aminophenyl)propanoyl]-L-lysyl-D-tryptophyl-L-phenylalanyl-]; (2-Aminoethyl)carbamic acid; UNII-R5H8897N95
EINECS	Contact for details

Quality Control

Our Pasireotide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity determination, and stringent control of related substances and residual solvents, ensuring compliance with ICH guidelines and relevant pharmacopeial standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Total)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.