Description

3-(5-Methyl-1,3,4-Oxadiazol-2-Yl)Benzenesulfonyl Chloride is a high-purity, specialized organic intermediate featuring a reactive sulfonyl chloride group attached to a substituted oxadiazole aromatic system. This compound is critical for synthetic chemists as a versatile building block for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel sulfonamide derivatives with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes where sulfonamide moieties are pharmacologically active.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that incorporate sulfonylurea or sulfonamide structures.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a reactive probe or labeling agent for studying protein interactions and enzyme activity due to its electrophilic sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	3-(5-Methyl-1,3,4-Oxadiazol-2-Yl)Benzenesulfonyl Chloride
CAS No.	388088-81-1
Molecular Formula	C9H7ClN2O3S
Molecular Weight	258.68 g/mol
Synonyms	3-(5-Methyl-1,3,4-oxadiazol-2-yl)benzenesulfonyl chloride; 3-(5-Methyl-1,3,4-oxadiazol-2-yl)benzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-3-(5-methyl-1,3,4-oxadiazol-2-yl)benzene; Benzenesulfonyl chloride, 3-(5-methyl-1,3,4-oxadiazol-2-yl)-; 388088-81-1; 3-(5-Methyl-[1,3,4]oxadiazol-2-yl)-benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-(5-Methyl-1,3,4-Oxadiazol-2-Yl)Benzenesulfonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.