Description

2-(Methylsulfonyl)-1-[6-(Trifluoromethyl)Pyridin-3-Yl]Ethanone is a high-value, multi-functional chemical intermediate characterized by its pyridine core and trifluoromethyl and methylsulfonyl substituents. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Biology & Proteomics: Employed as a reactive handle or linker in the design of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) developing proprietary compounds.

Basic Information

Product Name	2-(Methylsulfonyl)-1-[6-(Trifluoromethyl)Pyridin-3-Yl]Ethanone
CAS No.	386704-14-9
Molecular Formula	C9H6F3NO3S
Molecular Weight	265.21 g/mol
Synonyms	1-[6-(Trifluoromethyl)-3-pyridinyl]-2-(methylsulfonyl)ethanone; 2-(Methylsulfonyl)-1-(6-(trifluoromethyl)pyridin-3-yl)ethan-1-one; 2-Methanesulfonyl-1-[6-(trifluoromethyl)pyridin-3-yl]ethanone; 386704-14-9; Ethanone, 2-(methylsulfonyl)-1-[6-(trifluoromethyl)-3-pyridinyl]-
EINECS	Contact for details

Quality Control

Our 2-(Methylsulfonyl)-1-[6-(Trifluoromethyl)Pyridin-3-Yl]Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.