Description

6-(Trifluoromethyl)Pyridine-3-Carboxaldehyde is a versatile and high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an aldehyde group and a trifluoromethyl substituent on the pyridine ring, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is particularly valuable for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce the metabolically stable trifluoromethyl group into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to develop novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve lipophilicity and biological efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing characteristics.
• Fluorinated Liquid Crystal Synthesis: Acts as a building block for fluorinated mesogens used in display technologies.
• Custom Synthesis and Contract Research: A valuable reagent for custom synthesis houses and CROs (Contract Research Organizations) working on client-specific fluorinated targets.

Basic Information

Product Name	6-(Trifluoromethyl)Pyridine-3-Carboxaldehyde
CAS No.	386704-12-7
Molecular Formula	C7H4F3NO
Molecular Weight	175.11 g/mol
Synonyms	3-Formyl-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)nicotinaldehyde; 5-(Trifluoromethyl)pyridine-2-carboxaldehyde; 2-Pyridinecarboxaldehyde, 6-(trifluoromethyl)-; 6-Trifluoromethylpyridine-3-carbaldehyde; 6-Trifluoromethyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Pyridine-3-Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This compound is easily oxidized; prolonged exposure to air should be avoided. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.