Description

Tenofovir Related Compound 6 is a high-purity chemical reference standard and synthetic intermediate of significant importance in pharmaceutical research and development. Its primary value lies in its critical role in the quality control and analytical profiling of Tenofovir and its related pharmaceutical compounds. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require reliable reference materials for method development, validation, and impurity identification.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification and quantification of related substances in Tenofovir Active Pharmaceutical Ingredient (API) and finished drug products.
• Analytical Method Development: Serves as a critical impurity marker in developing and validating High-Performance Liquid Chromatography (HPLC) and other chromatographic methods for quality control laboratories.
• Process Chemistry Research: Acts as a key intermediate or impurity standard in studying and optimizing the synthetic pathways for Tenofovir and its prodrugs.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., for FDA, EMA) by providing characterized impurity standards required for stability studies and specification setting.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for pharmacological studies and metabolic profiling related to nucleotide reverse transcriptase inhibitors.

Basic Information

Product Name	Tenofovir Related Compound 6
CAS No.	383365-04-6
Molecular Formula	C9H14N5O4P
Molecular Weight	287.21 g/mol
Synonyms	Tenofovir Impurity 6; (R)-9-(2-Phosphonomethoxypropyl)adenine Impurity 6; PMPA Related Compound 6; (R)-PMPA Impurity 6; GS 1278 Impurity; 9-[(R)-2-(Phosphonomethoxy)propyl]adenine Related Substance 6; Viread Impurity 6; TDF Related Compound 6
EINECS	Contact for details

Quality Control

Our Tenofovir Related Compound 6 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with relevant standards for pharmaceutical reference materials. Our commitment is to supply materials that meet the exacting requirements of modern analytical and regulatory laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15°C and 25°C (59°F and 77°F), in a dry environment. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.