Description

Pyroxamide CAS NO 382180-17-8 is a potent and selective small molecule compound belonging to the class of histone deacetylase (HDAC) inhibitors. This compound is of significant interest for its role in modulating gene expression and cellular processes, making it a valuable research tool in oncology and epigenetics. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in drug discovery and development.

Application

• Biochemical Research: Used as a reference standard and active agent in studies investigating histone deacetylase (HDAC) enzyme activity and inhibition mechanisms.
• Oncology Research: Employed in in vitro and in vivo models to study its effects on cancer cell proliferation, differentiation, and apoptosis.
• Epigenetics Studies: A key tool for exploring chromatin remodeling, gene expression regulation, and the role of acetylation in various disease states.
• Pharmaceutical Development: Serves as a lead compound or intermediate in the synthesis and development of novel therapeutic agents targeting HDACs.
• Cell Biology: Applied in assays to understand cellular differentiation and the impact of HDAC inhibition on specific signaling pathways.

Basic Information

Product Name	Pyroxamide
CAS No.	382180-17-8
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	Pyroxamide; N-Hydroxy-3-[3-(methylamino-methyl)phenyl]-2E-propenamide; CI-994; PD 123654; Goe 5549; Tacedinaline; Acetyldinaline
EINECS	Contact for details

Quality Control

Our Pyroxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to moisture and light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.