

share
2-Methyl-4-(Trifluoromethoxy)Benzenesulfonylchloride CAS NO 376637-84-2
Unit Price:
CAS No.:376637-84-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Methyl-4-(Trifluoromethoxy)Benzenesulfonylchloride is a high-value, multi-functional sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride group, which enables the efficient introduction of the sulfonamide moiety, a key pharmacophore and functional group in numerous industrial applications. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
- Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
- Material Science: Used in the production of specialty polymers, dyes, and functional materials requiring sulfonamide linkages.
- Chemical Research: Versatile reagent for medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.
- Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.
Basic Information
| Product Name | 2-Methyl-4-(Trifluoromethoxy)Benzenesulfonylchloride |
| CAS No. | 376637-84-2 |
| Molecular Formula | C8H6ClF3O3S |
| Molecular Weight | 274.65 g/mol |
| Synonyms | 2-Methyl-4-(trifluoromethoxy)benzenesulfonyl chloride; 4-(Trifluoromethoxy)-2-methylbenzenesulfonyl chloride; 1-Methyl-2-(trifluoromethoxy)-5-sulfonylchloridebenzene; α,α,α-Trifluoro-2-methyl-4-methoxybenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-methyl-4-(trifluoromethoxy)-; 2-Methyl-4-trifluoromethoxybenzenesulfonyl chloride |
| EINECS | Contact for details |
Quality Control
Our 2-Methyl-4-(Trifluoromethoxy)Benzenesulfonylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures batch-to-batch consistency, which is critical for your research and development processes.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
Hot Related Products


Tosyl Chloride CAS NO 98-59-9


Rarechem Al Bf 1329 CAS NO 57381-36-9


2-Diazo-1-Naphthol-5-Sulfonyl Chloride CAS NO 3770-97-6


1-Hexadecanesulfonyl Chloride CAS NO 38775-38-1


3,5-Dimethylbenzenesulfonyl Chloride CAS NO 2905-27-3


Dimethylsulfamoyl Chloride CAS NO 13360-57-1


n-Bromosuccinimide CAS NO 128-08-5


Diethylsulfamoyl Chloride CAS NO 20588-68-5


2-Methyl-5-Nitrobenzenesulfonyl Chloride CAS NO 121-02-8


3-Nitrobenzenesulfonyl Chloride CAS NO 121-51-7


Methanesulfonyl Chloride CAS NO 124-63-0


o-Toluenesulfonyl Chloride CAS NO 133-59-5


2-Chloro-5-(Chlorosulfonyl)-Benzoicaci CAS NO 137-64-4


4-Ethoxy-Benzenesulfonyl Chloride CAS NO 1132-17-8


Benzenesulfonyl Chloride, 4-(2-Methylpropoxy)- CAS NO 1138-54-1


Akos B006681 CAS NO 1204-32-6


Tfec CAS NO 1513-87-7


4-Methyl-3-Nitrobenzenesulfonyl Fluoride CAS NO 1535-47-3


2-Chloroethanesulfonyl Chloride CAS NO 1622-32-8


4-Phenoxybenzenesulfonyl Chloride CAS NO 1623-92-3
Why choose US
Trusted Manufacturer
With our own production facilities, we ensure consistent quality, reliable supply, and full traceability.
Rigorous Quality Assurance
Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
Advanced R&D Expertise
Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.






