Description

5-Chloro-2-Fluoro-3-Methylpyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which enables precise molecular modifications essential for developing novel active ingredients. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Used in the development of specialty chemicals, liquid crystals, and advanced polymeric materials.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis: Employed by contract research organizations (CROs) and CDMOs for client-specific molecule development and scale-up projects.

Basic Information

Product Name	5-Chloro-2-Fluoro-3-Methylpyridine
CAS No.	375368-84-6
Molecular Formula	C6H5ClFN
Molecular Weight	145.56 g/mol
Synonyms	2-Fluoro-5-chloro-3-methylpyridine; 3-Methyl-5-chloro-2-fluoropyridine; 5-Chloro-2-fluoro-3-picoline; 2-Fluoro-3-methyl-5-chloropyridine; 375368-84-6; Pyridine, 5-chloro-2-fluoro-3-methyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluoro-3-Methylpyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.