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3-Fluoro-2-Methoxy-6-Picoline CAS NO 375368-80-2


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CAS No.:375368-80-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Fluoro-2-Methoxy-6-Picoline is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both fluorine and methoxy substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
  • Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and steric properties.
  • Chemical Biology Probes: Utilized as a building block for fluorinated analogs of biologically active molecules, aiding in metabolic studies and mechanism-of-action research.

Basic Information

Product Name 3-Fluoro-2-Methoxy-6-Picoline
CAS No. 375368-80-2
Molecular Formula C7H8FNO
Molecular Weight 141.14 g/mol
Synonyms 2-Methoxy-3-fluoro-6-methylpyridine; 6-Methyl-3-fluoro-2-methoxypyridine; 3-Fluoro-2-methoxy-6-methylpyridine; 3-Fluoro-2-methoxy-6-picoline; 2-Methoxy-3-fluoro-6-picoline; 3-Fluoro-6-methyl-2-methoxypyridine
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Quality Control

Every batch of 3-Fluoro-2-Methoxy-6-Picoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder or solid
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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