Description

4-Methylpyridine-3-Sulfonyl Chloride CAS NO 372198-42-0 is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules with high efficiency. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients, intermediates, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require the sulfonyl moiety for biological activity.
• Material Science: Employed in the creation of specialty polymers and functional materials where sulfonyl groups modify physical or chemical properties.
• Chemical Research & Development: Serves as a fundamental reagent in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of certain sulfonated dyes and colorants.

Basic Information

Product Name	4-Methylpyridine-3-Sulfonyl Chloride
CAS No.	372198-42-0
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	3-(Chlorosulfonyl)-4-methylpyridine; 4-Methyl-3-pyridinesulfonyl chloride; 4-Methylpyridine-3-sulfonyl chloride; 4-Picoline-3-sulfonyl chloride; 3-Pyridinesulfonyl chloride, 4-methyl-; 4-Methyl-3-sulfonylchloropyridine
EINECS	Contact for details

Quality Control

Our 4-Methylpyridine-3-Sulfonyl Chloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.