Description

Norneosildenafil CAS NO 371959-09-0 is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest for its role in the synthesis and development of active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers engaged in advanced synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of specialized active pharmaceutical ingredients (APIs).
• Research & Development: Used in biochemical and pharmacological research to study structure-activity relationships (SAR).
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.

Basic Information

Product Name	Norneosildenafil
CAS No.	371959-09-0
Molecular Formula	C22H30N6O4S
Molecular Weight	474.58 g/mol
Synonyms	N-Desmethyl Sildenafil; UK-103,320; 5-[2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; Nor-Sildenafil; Desmethylsildenafil; Sildenafil Impurity F
EINECS	Contact for details

Quality Control

Our Norneosildenafil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-grade specifications for research and pharmaceutical use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.