Description

2-Methyl-2,3-Dihydrobenzofuran-5-Sulfonyl Chloride is a high-value, reactive sulfonyl chloride derivative, primarily utilized as a critical synthetic intermediate in advanced organic synthesis. Its core value lies in its ability to act as a versatile electrophile for introducing the sulfonyl functional group, enabling the construction of complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require the sulfonyl moiety for biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of specialty polymers and functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying protein function and enzyme activity.
• Dye and Pigment Manufacturing: Intermediate for producing sulfonated dyes and specialty colorants with enhanced solubility and fastness properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Methyl-2,3-Dihydrobenzofuran-5-Sulfonyl Chloride
CAS No.	369638-66-4
Molecular Formula	C9H9ClO3S
Molecular Weight	232.68 g/mol
Synonyms	5-(Chlorosulfonyl)-2-methyl-2,3-dihydrobenzofuran; 2-Methyl-2,3-dihydrobenzofuran-5-sulfonyl chloride; 2-Methyl-2,3-dihydro-5-benzofuransulfonyl chloride; 2,3-Dihydro-2-methyl-5-benzofuransulfonyl chloride; 369638-66-4; 2-Methyl-2,3-dihydrobenzofurane-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2,3-Dihydrobenzofuran-5-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.