Description

2-(3,5-Bis(Trifluoromethyl)Phenyl)Acetaldehyde is a high-value fluorinated aromatic aldehyde building block, prized for its unique electronic properties imparted by the trifluoromethyl groups. This compound is essential for synthesizing advanced pharmaceutical intermediates and agrochemicals, where its structure facilitates the introduction of lipophilic and electron-withdrawing motifs. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology, where the CF3 groups can enhance metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its ability to act as a versatile linker for constructing complex, bioactive molecules.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the creation of fluorinated polymers, liquid crystals, and organic electronic materials to modify solubility and electronic characteristics.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes due to the distinct properties of the fluorinated aromatic ring.

Basic Information

Product Name	2-(3,5-Bis(Trifluoromethyl)Phenyl)Acetaldehyde
CAS No.	369625-84-3
Molecular Formula	C10H5F6O
Molecular Weight	246.14 g/mol
Synonyms	2-[3,5-Bis(trifluoromethyl)phenyl]acetaldehyde; 3,5-Bis(trifluoromethyl)phenylacetaldehyde; 2-(3,5-Bis(trifluoromethyl)phenyl)ethanal; α,α,α,α',α',α'-Hexafluoro-3,5-xylylacetaldehyde; 369625-84-3; 2-(3,5-di(trifluoromethyl)phenyl)acetaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-(3,5-Bis(Trifluoromethyl)Phenyl)Acetaldehyde is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) including purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents and strong bases. Due to its sensitivity, allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.