Description

4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Sulfonyl Chloride is a high-purity sulfonyl chloride derivative, a critical building block in modern organic synthesis. This compound matters because it serves as a versatile and reactive intermediate for introducing the sulfonamide pharmacophore, enabling the development of novel active molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of biologically active sulfonamide-containing compounds for drug discovery programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that leverage sulfonamide chemistry.
• Material Science Research: Employed in the creation of specialty polymers and functional materials with tailored properties.
• Chemical Biology Probes: Acts as a reactive handle for labeling proteins or other biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules at various scales.

Basic Information

Product Name	4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Sulfonyl Chloride
CAS No.	368869-93-6
Molecular Formula	C9H10ClNO3S
Molecular Weight	247.70 g/mol
Synonyms	7-(Chlorosulfonyl)-4-methyl-3,4-dihydro-2H-1,4-benzoxazine; 4-Methyl-2H-1,4-benzoxazine-7-sulfonyl chloride, 3,4-dihydro-; 3,4-Dihydro-4-methyl-2H-1,4-benzoxazine-7-sulfonyl chloride; 4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-sulfonyl chloride; Benzoxazine-7-sulfonyl chloride derivative; CAS 368869-93-6
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) with full batch traceability are provided to guarantee consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.