Description

Ethyl 6-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylate is a high-value fluorinated heterocyclic building block, essential for advanced pharmaceutical and agrochemical research and development. Its core value lies in the imidazopyridine scaffold, which is a privileged structure in medicinal chemistry, combined with a strategically placed fluorine atom and an ester group for further synthetic manipulation. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, especially those containing the imidazo[1,2-a]pyridine core.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to enhance potency, selectivity, and metabolic stability of potential therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating new crop protection agents and pesticides with improved efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Material Science Research: Investigated as a component for advanced organic electronic materials due to its conjugated heterocyclic system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	Ethyl 6-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	367500-93-4
Molecular Formula	C10H9FN2O2
Molecular Weight	208.19 g/mol
Synonyms	6-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Ethyl 6-fluoroimidazo[1,2-a]pyridine-2-carboxylate; 2-Carbethoxy-6-fluoroimidazo[1,2-a]pyridine; 6-Fluoro-2-ethoxycarbonylimidazo[1,2-a]pyridine; Ethyl 6-fluoro-1H-imidazo[1,2-a]pyridine-2-carboxylate; 367500-93-4; AI3-32462
EINECS	Contact for details

Quality Control

Our Ethyl 6-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.