Description

Ot-R Antagonist 1 CAS NO 364071-17-0 is a high-purity, small molecule chemical compound designed for advanced research and development. This compound serves as a potent and selective antagonist for the orexin receptor (Ot-R), making it a critical tool for investigating neurological pathways related to sleep, appetite, and addiction. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on central nervous system (CNS) drug discovery and neuropharmacology studies.

Application

• Neurological Research: Fundamental studies on orexin receptor signaling pathways and their role in sleep-wake regulation.
• Drug Discovery Programs: A key reference standard and pharmacological tool in the development of novel therapeutics for insomnia and narcolepsy.
• Preclinical Studies: Used in in vitro and in vivo models to evaluate the efficacy and mechanism of action of potential CNS-targeting drugs.
• Biochemical Assay Development: Serves as a control compound in high-throughput screening (HTS) assays for identifying new orexin receptor modulators.
• Academic Pharmacology: Employed in university laboratories for teaching and advanced research into G-protein-coupled receptor (GPCR) function.

Basic Information

Product Name	Ot-R Antagonist 1
CAS No.	364071-17-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Orexin Receptor Antagonist 1; OX1R Antagonist; Hypocretin Receptor Antagonist; CNS Active Compound; Research Compound 364071-17-0; Ot-R Blocker; Neuropharmacological Research Agent
EINECS	Contact for details

Quality Control

Every batch of Ot-R Antagonist 1 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with standards expected for research-grade fine chemicals. A comprehensive Certificate of Analysis (COA), detailing results for purity (HPLC), identity (NMR, MS), and other critical parameters, is provided with each shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.