Description

1,3,4-Thiadiazole-2-Sulfonyl Chloride is a versatile and reactive heterocyclic sulfonyl chloride derivative. This compound serves as a critical building block in advanced organic synthesis, enabling the introduction of the 1,3,4-thiadiazole sulfonamide moiety. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, where its unique scaffold is valued for creating compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes where sulfonamide groups are pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole ring.
• Material Science Research: Employed in the creation of specialty polymers and functional materials that require sulfonamide linkages or heterocyclic components.
• Chemical Biology Probes: Acts as a reactive handle for labeling or modifying biomolecules in proteomics and biochemical research.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing complex ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	1,3,4-Thiadiazole-2-Sulfonyl Chloride
CAS No.	362521-36-6
Molecular Formula	C2HN2O2S2Cl
Molecular Weight	184.62 g/mol
Synonyms	2-Sulfonylchloride-1,3,4-thiadiazole; 1,3,4-Thiadiazole-2-sulfonyl chloride; 1,3,4-Thiadiazol-2-ylsulfonyl chloride; 2-Chlorosulfonyl-1,3,4-thiadiazole; Thiadiazole-2-sulfonyl chloride; 1,3,4-Thiadiazole sulfonyl chloride; 2-(Chlorosulfonyl)-1,3,4-thiadiazole
EINECS	Contact for details

Quality Control

Our 1,3,4-Thiadiazole-2-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.