Description

n-Demethyl Cocaethylene Hydrochloride is a high-purity chemical reference standard and synthetic intermediate of significant interest in analytical and research chemistry. This compound is critical for forensic analysis, toxicology studies, and the development of detection methodologies for controlled substance metabolites. It serves as an essential tool for researchers and quality control laboratories in pharmaceutical development, clinical diagnostics, and regulatory compliance sectors requiring precise analytical standards.

Application

• Analytical Reference Standard: Primary use as a certified reference material (CRM) for the qualitative and quantitative analysis of metabolites in forensic and clinical toxicology.
• Forensic Science & Toxicology: Critical for method development, validation, and calibration of analytical instruments (LC-MS/MS, GC-MS) used in drug testing and post-mortem investigations.
• Metabolite Research: Used in pharmacological and pharmacokinetic studies to understand the biotransformation pathways of specific controlled substances.
• Pharmaceutical Impurity Profiling: Employed in the identification and quantification of potential impurity peaks during the development and quality control of related pharmaceutical compounds.
• Diagnostic Kit Development: Serves as a key antigen or hapten in the development of immunoassays and rapid test kits for substance abuse screening.
• Academic & Institutional Research: Used in universities and research institutes for studies related to neurochemistry, addiction science, and analytical method development.

Basic Information

Product Name	n-Demethyl Cocaethylene Hydrochloride
CAS No.	362044-01-7
Molecular Formula	C19H27NO4 • HCl
Molecular Weight	369.88 g/mol (Free base: 333.43 g/mol)
Synonyms	Norcocaethylene Hydrochloride; Benzoylecgonine Ethyl Ester, Nor-; 3β-Hydroxy-2β-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-1α-carboxylic Acid Ethyl Ester, Nor-, Hydrochloride; Cocaethylene N-demethylated HCl; Cocaethylene Nor- Hydrochloride; 1-Carboxy-2-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol Ethyl Ester, Nor-, Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of n-Demethyl Cocaethylene Hydrochloride is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous testing, including advanced chromatographic and spectroscopic methods, to comply with the high standards required for analytical reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.