Description

Z-2-Fluoro-3-(3-Pyridyl)Acrylic Acid is a high-value fluorinated pyridine derivative and a key synthetic intermediate in modern organic chemistry. This compound is crucial for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals due to its unique structural motif. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized monomers for advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorinated analogs for studying enzyme mechanisms and metabolic pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds for client R&D projects.

Basic Information

Product Name	Z-2-Fluoro-3-(3-Pyridyl)Acrylic Acid
CAS No.	359435-42-0
Molecular Formula	C8H6FNO2
Molecular Weight	167.14 g/mol
Synonyms	(Z)-2-Fluoro-3-(pyridin-3-yl)acrylic acid; (Z)-2-Fluoro-3-(3-pyridinyl)-2-propenoic acid; 2-Fluoro-3-(3-pyridyl)acrylic acid (Z-isomer); 3-Pyridineacrylic acid, 2-fluoro-, (Z)-; Z-2-Fluoro-3-pyridin-3-yl-acrylic acid; (Z)-α-Fluoro-3-pyridineacrylic acid
EINECS	Contact for details

Quality Control

Every batch of Z-2-Fluoro-3-(3-Pyridyl)Acrylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isomeric integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee batch-to-batch consistency and traceability for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (Z-Isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.