Description

4-Chloro-2-Methylphenol-3,5,6-D3 is a deuterium-labeled isotopologue of 4-chloro-2-methylphenol, a key phenolic compound. This labeled version is essential for use as an internal standard in advanced analytical techniques, ensuring precise quantification and reliable data in complex matrices. It is primarily required by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental science sectors for method development and trace analysis.

Application

• Internal Standard for Mass Spectrometry (MS): Used in LC-MS and GC-MS analysis for the accurate quantification of 4-chloro-2-methylphenol and related compounds in pharmacokinetic and metabolic studies.
• Pharmaceutical Research: Critical for drug metabolism and disposition (DMPK) studies, enabling the tracking of parent compounds and metabolites with high specificity.
• Environmental Analysis: Employed in the detection and measurement of chlorinated phenols as pollutants in water, soil, and industrial waste samples.
• Agrochemical Development: Serves as a tracer in the research of pesticides and herbicides to study degradation pathways and environmental fate.
• Chemical Synthesis Research: Used as a labeled building block in synthetic chemistry to investigate reaction mechanisms and isotopic effects.
• Forensic and Toxicology Testing: Aids in the precise identification and quantification of phenolic compounds in forensic analyses and toxicological screenings.

Basic Information

Product Name	4-Chloro-2-Methylphenol-3,5,6-D3
CAS No.	358731-13-2
Molecular Formula	C7H4D3ClO
Molecular Weight	145.60 g/mol (approx.)
Synonyms	4-Chloro-2-methylphenol-d3; 2-Methyl-4-chlorophenol-3,5,6-d3; 4-Chloro-o-cresol-d3; Deuterated 4-Chloro-2-methylphenol; p-Chloro-o-cresol-d3; 3,5,6-Trideutero-4-chloro-2-methylphenol; 4-Chloro-2-(2H3)methylphenol; 4-Cl-2-MePhenol-d3
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality protocols to ensure isotopic purity and chemical integrity, which are critical for analytical accuracy. Each batch is characterized by NMR and mass spectrometry to confirm deuterium incorporation and chemical purity. Certificates of Analysis (COA) detailing isotopic purity (e.g., D ≥ 98%), chemical purity (by HPLC or GC), and other relevant specifications are provided to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (Assay)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.