Description

3-Pyridinecarboxylic Acid, 6-[4-(Trifluoromethyl)Phenyl]-, Methyl Ester is a high-value trifluoromethylated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a pyridine core and a trifluoromethylphenyl group, makes it an essential intermediate for creating compounds with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers used in catalysis and specialty polymers.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.
• Liquid Crystal & OLED Materials: Potential intermediate for electronic materials requiring specific aromatic and fluorinated components.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 6-[4-(Trifluoromethyl)Phenyl]-, Methyl Ester
CAS No.	356058-34-9
Molecular Formula	C14H10F3NO2
Molecular Weight	281.23 g/mol
Synonyms	Methyl 6-[4-(trifluoromethyl)phenyl]nicotinate; Methyl 6-(4-(trifluoromethyl)phenyl)pyridine-3-carboxylate; 6-(4-Trifluoromethylphenyl)nicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 6-[4-(trifluoromethyl)phenyl]-, methyl ester; Nicotinic acid, 6-[4-(trifluoromethyl)phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinecarboxylic Acid, 6-[4-(Trifluoromethyl)Phenyl]-, Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive R&D applications. We employ advanced analytical techniques, including HPLC, GC, and NMR, for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.