Description

6-(4-Trifluoromethyl-Phenyl)-Pyridine-3-Carbaldehyde is a high-purity, versatile organic building block characterized by its pyridine core and trifluoromethylphenyl substituent. This compound is of significant commercial interest due to its role as a key intermediate in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and protein interactions in biochemical research.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	6-(4-Trifluoromethyl-Phenyl)-Pyridine-3-Carbaldehyde
CAS No.	356058-14-5
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	6-[4-(Trifluoromethyl)phenyl]pyridine-3-carbaldehyde; 3-Pyridinecarboxaldehyde, 6-[4-(trifluoromethyl)phenyl]-; 6-(4-Trifluoromethylphenyl)nicotinaldehyde; 6-(4-Trifluoromethylphenyl)-3-pyridinecarboxaldehyde; 6-(4-Trifluoromethylphenyl)pyridine-3-carboxaldehyde; 6-(p-Trifluoromethylphenyl)nicotinaldehyde; 356058-14-5
EINECS	Contact for details

Quality Control

Our 6-(4-Trifluoromethyl-Phenyl)-Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.