Description

4-Methoxy-1-Piperidinesulfonyl Chloride (Saltdata: Free) is a specialized sulfonyl chloride derivative, a key reactive intermediate in modern organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the efficient introduction of the 4-methoxypiperidine-1-sulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals. The CAS number for this compound is 355849-73-9.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the sulfonamide group is a common pharmacophore.
• Chemical Biology Probe Development: Employed to create sulfonamide-based probes for studying enzyme function and protein-protein interactions.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	4-Methoxy-1-Piperidinesulfonyl Chloride (Saltdata: Free)
CAS No.	355849-73-9
Molecular Formula	C6H12ClNO3S
Molecular Weight	213.68 g/mol
Synonyms	1-(Chlorosulfonyl)-4-methoxypiperidine; 4-Methoxypiperidine-1-sulfonyl chloride; 4-Methoxy-1-piperidinesulfonyl chloride; 4-MOPSC; 1-Piperidinesulfonyl chloride, 4-methoxy-; 355849-73-9
EINECS	Contact for details

Quality Control

Our 4-Methoxy-1-Piperidinesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. Standard quality control includes HPLC assay, identity confirmation (IR, NMR), and tests for key impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment. We support cGMP and ISO standards for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider refrigeration (2-8°C) under desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.