Description

Ethyl-D-Erythro-Sphingosinate Hydrochloride is a high-purity, synthetic sphingolipid derivative, specifically the ethyl ester hydrochloride salt of D-erythro-sphingosine. This compound serves as a critical pharmaceutical intermediate and biochemical research tool for studying cellular signaling pathways, particularly those involving ceramide metabolism and apoptosis. It is essential for researchers and manufacturers in pharmaceutical development, life science research, and advanced material science who require a reliable and well-characterized building block for sphingolipid synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex sphingolipids and ceramide analogs for drug discovery programs targeting cancer, inflammation, and metabolic disorders.
• Biochemical Research: Used as a standard or substrate in enzymatic assays to study sphingolipid-metabolizing enzymes like ceramidases and sphingosine kinases.
• Cell Biology Studies: Employed to investigate the role of sphingolipids in cell signaling, membrane structure, and programmed cell death (apoptosis).
• Lipidomics: Serves as a reference compound in mass spectrometry-based lipid profiling and quantification studies.
• Cosmeceutical R&D: Explored as a potential active ingredient in advanced skincare formulations targeting skin barrier function and cellular renewal.
• Academic Research: A fundamental reagent for universities and research institutes studying lipid biochemistry and cell membrane dynamics.

Basic Information

Product Name	Ethyl-D-Erythro-Sphingosinate Hydrochloride
CAS No.	355803-79-1
Molecular Formula	C20H42ClNO3
Molecular Weight	379.99 g/mol
Synonyms	D-erythro-Sphingosine ethyl ester hydrochloride; (2S,3R,4E)-2-Amino-4-octadecene-1,3-diol ethyl ester hydrochloride; Ethyl (2S,3R,4E)-2-amino-4-octadecene-1,3-diol hydrochloride; Sphingosine ethyl ester HCl; D-erythro-C18-Sphingosine ethyl ester hydrochloride; Ethyl sphingosinate hydrochloride; 4E-D-erythro-Sphingosine ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl-D-Erythro-Sphingosinate Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing including HPLC for assay and chiral purity, NMR for structural confirmation, and tests for residual solvents and moisture. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and high-grade research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% D-erythro isomer
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.