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n-Butyldeoxymannojirimycin, Hydrochloride CAS NO 355012-88-3
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CAS No.:355012-88-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
n-Butyldeoxymannojirimycin, Hydrochloride is a potent and selective α-mannosidase inhibitor, a key compound in glycobiology research and pharmaceutical development. Its primary value lies in its ability to modulate N-linked glycan processing, making it an essential tool for studying glycosylation-related biological pathways and diseases. This high-purity biochemical is critical for researchers and developers in the pharmaceutical, biotechnology, and life science sectors investigating metabolic disorders, viral infections, and cancer.
Application
- Glycobiology Research: A fundamental tool for studying the role of α-mannosidases in N-linked oligosaccharide biosynthesis and processing.
- Antiviral Agent Development: Investigated for its potential to inhibit the replication of enveloped viruses, such as hepatitis B and C, by disrupting viral glycoprotein maturation.
- Oncology Research: Used in studies targeting aberrant glycosylation pathways associated with tumor metastasis and progression.
- Metabolic Disorder Studies: Applied in research on congenital disorders of glycosylation (CDGs) and other lysosomal storage diseases.
- Pharmaceutical Intermediate: Serves as a key synthetic intermediate or reference standard in the development of novel therapeutic agents.
- Biochemical Assay Standard: Used as a precise inhibitor standard in enzymatic assays to determine α-mannosidase activity.
Basic Information
| Product Name | n-Butyldeoxymannojirimycin, Hydrochloride |
| CAS No. | 355012-88-3 |
| Molecular Formula | C14H28N2O4 • HCl |
| Molecular Weight | 324.85 g/mol (Free base: 288.38) |
| Synonyms | N-Butyl-deoxymannojirimycin HCl; N-Butyl-DMJ hydrochloride; 1,5-Dideoxy-1,5-imino-N-butyl-D-mannitol hydrochloride; α-Mannosidase Inhibitor NB-DNJ HCl; MDL 28,574; Bu-DMJ HCl; Deoxynojirimycin Derivative; Iminosugar Inhibitor |
| EINECS | Contact for details |
Quality Control
Our n-Butyldeoxymannojirimycin, Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality guidelines to support our global customer base in pharmaceutical and advanced research applications.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Water Content (KF) | ≤1.0% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
| Related Substances (HPLC) | Total impurities ≤2.0% |
| Specific Rotation | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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