Description

Verapamilethyl Methanethiosulfonate, Bromide is a specialized chemical intermediate featuring a methanethiosulfonate functional group, which is highly reactive and valuable for targeted chemical modifications. This compound is crucial for researchers and manufacturers requiring precise, site-specific bioconjugation or the introduction of disulfide bonds in complex molecular systems. It is primarily utilized in advanced pharmaceutical research, particularly in the development of prodrugs and targeted therapies, as well as in biochemical studies involving protein labeling and structure-function analysis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and prodrugs, especially those targeting cardiovascular or neurological pathways.
• Bioconjugation Reagent: Used for the site-specific modification of proteins, antibodies, and peptides to create stable conjugates for drug delivery and diagnostics.
• Chemical Biology Research: A critical tool for studying protein structure, function, and interactions through controlled disulfide bridge formation or thiol labeling.
• Prodrug Development: Enables the design of inactive drug precursors that are activated under specific physiological conditions.
• Material Science: Potential use in creating functionalized surfaces or polymers with specific reactive sites.

Basic Information

Product Name	Verapamilethyl Methanethiosulfonate, Bromide
CAS No.	353270-25-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Verapamil ethyl methanethiosulfonate bromide; 2-[3,4-Dimethoxyphenyl)ethyl]methylamino]ethyl 3,4-dimethoxy-α-isopropyl-α-[(methylthio)thiocarbonyl]aminomethyl]benzenepropanentrile methanethiosulfonate bromide; (RS)-Verapamil methanethiosulfonate derivative; MTS-Verapamil derivative; Thiol-reactive verapamil analog; S-Methyl methanethiosulfonate verapamil conjugate
EINECS	Contact for details

Quality Control

Our Verapamilethyl Methanethiosulfonate, Bromide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. Handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.