Description

3-Iodobenzylzinc Bromide 0.5M Solution is a versatile organozinc reagent, a key building block for modern synthetic chemistry. This solution offers a convenient and reliable source of the 3-iodobenzyl anion equivalent, enabling critical carbon-carbon bond formation under mild conditions. It is essential for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and advanced material science, where precision and reproducibility are paramount.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for Negishi cross-coupling reactions to construct complex biaryl and alkyl-aryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by introducing the 3-iodobenzyl moiety into target molecules.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science: Employed in the functionalization of polymers and the creation of organic electronic materials through precise molecular engineering.
• Chemical Biology & Probe Development: Facilitates the site-specific incorporation of iodobenzyl groups into biomolecules or molecular probes for imaging and diagnostic applications.
• Custom Fine Chemical Manufacturing: Enables contract research and manufacturing organizations (CROs/CMOs) to perform bespoke synthesis for client projects requiring benzylation or cross-coupling steps.

Basic Information

Product Name	3-Iodobenzylzinc Bromide 0.5M Solution
CAS No.	352530-31-5
Molecular Formula	C7H6BrIZn
Molecular Weight	352.33 g/mol
Synonyms	1-(Bromozincio)methyl-3-iodobenzene; (3-Iodobenzyl)zinc bromide; Zinc, bromo(3-iodophenyl)methyl-; 3-Iodobenzylzinc bromide solution; (3-Iodobenzyl)zinc bromide solution; Benzene, 1-(bromozincio)methyl-3-iodo-; Organozinc reagent 352530-31-5
EINECS	Contact for details

Quality Control

Every batch of our 3-Iodobenzylzinc Bromide 0.5M Solution is manufactured and analyzed under strict quality protocols to ensure consistency and reliability for your critical syntheses. We employ advanced analytical techniques, including titration and GC/HPLC, to verify concentration, purity, and the absence of deleterious impurities. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. The product is moisture-sensitive (hygroscopic) and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and humidity. For long-term stability, storage at or below -20°C is recommended.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	0.5 M in specified solvent (e.g., THF)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Solvent Content (GC)	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.