Description

4-Iodobenzylzinc Bromide 0.5M Solution is a versatile organozinc reagent, specifically a benzylzinc halide, supplied as a standardized 0.5 molar solution for precise stoichiometric control in advanced synthesis. This compound matters as a critical building block for introducing the 4-iodobenzyl moiety in cross-coupling reactions, enabling efficient carbon-carbon bond formation under mild conditions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for Negishi and related cross-coupling reactions to create novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides by constructing specific aromatic frameworks.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Material Science: Employed in the synthesis of organic electronic materials, such as OLED precursors and conductive polymers, where the iodobenzyl group is integral.
• Fine Chemical Manufacturing: Facilitates the production of high-value, complex aromatic compounds for flavors, fragrances, and specialty chemicals.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and scaling up coupling reactions from lab to pilot plant.

Basic Information

Item	Detail
Product Name	4-Iodobenzylzinc Bromide 0.5M Solution
CAS No.	352530-30-4
Molecular Formula	C7H6BrIZn
Molecular Weight	352.33 g/mol
Synonyms	(4-Iodobenzyl)zinc bromide; Zinc, bromo(4-iodophenyl)methyl-; 4-Iodobenzylzinc bromide solution; (4-Iodophenylmethyl)zinc bromide; p-Iodobenzylzinc bromide; Benzylzinc bromide, 4-iodo-; Organozinc reagent 4-IodobenzylZnBr
EINECS	Contact for details

Quality Control

Every batch of our 4-Iodobenzylzinc Bromide 0.5M Solution is manufactured and tested under stringent quality management systems. We ensure consistent molarity, purity, and performance through rigorous analytical protocols, including titration for zinc content and GC/HPLC analysis for solvent and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to guarantee it meets your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dedicated, well-ventilated area. Due to its properties of being easily oxidized and highly volatile, the solution must be handled under inert conditions using standard Schlenk or glovebox techniques to maintain stability and prevent concentration changes. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Concentration	0.5 M in THF (Typical)
Assay (Zn Titration)	0.45 - 0.55 M
Purity (GC)	≥ 95% (on solvent-free basis)
Water Content (Karl Fischer)	≤ 0.1%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.