Description

4-Bromo-3-Fluorobenzenesulfonyl Chloride is a high-purity, multi-functional organosulfur building block essential for advanced chemical synthesis. This compound matters because it serves as a critical precursor for introducing the sulfonyl chloride functional group into complex molecules, enabling the creation of sulfonamides and other valuable derivatives. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Employed in the creation of specialty polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Acts as a reagent for labeling and modifying biomolecules to study protein function and interactions.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Academic & Industrial R&D: Fundamental research reagent in organic chemistry for methodology development and exploring new reaction pathways.

Basic Information

Product Name	4-Bromo-3-Fluorobenzenesulfonyl Chloride
CAS No.	351003-51-5
Molecular Formula	C6H3BrClFO2S
Molecular Weight	273.51 g/mol
Synonyms	3-Fluoro-4-bromobenzenesulfonyl chloride; 1-Bromo-2-fluoro-4-(chlorosulfonyl)benzene; 4-Bromo-3-fluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-3-fluoro-; p-Bromo-m-fluorobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-3-Fluorobenzenesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A detailed Certificate of Analysis (COA) including purity (HPLC/GC), identity confirmation (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.