Description

4-Bromo-2,6-Dimethylbenzene-1-Sulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the sulfonyl chloride group acts as a versatile electrophile for forming sulfonamides and sulfonate esters, while the bromo substituent offers a handle for further cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for creating sulfonamide-based therapeutics with potential antibacterial, diuretic, or protease inhibitory activity.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the sulfonyl moiety can contribute to biological activity and selectivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, dyes, and liquid crystals.
• Chemical Biology & Proteomics: Acts as a reactive probe or labeling agent for modifying proteins and studying biological pathways due to its electrophilic sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, high-value molecules for clients.

Basic Information

Product Name	4-Bromo-2,6-Dimethylbenzene-1-Sulfonyl Chloride
CAS No.	351003-50-4
Molecular Formula	C8H8BrClO2S
Molecular Weight	283.57 g/mol
Synonyms	4-Bromo-2,6-dimethylbenzenesulfonyl chloride; 2,6-Dimethyl-4-bromobenzenesulfonyl chloride; 1-Bromo-3,5-dimethyl-4-sulfonylchloridobenzene; 4-Bromo-2,6-xylenesulfonyl chloride; p-Bromo-2,6-dimethylbenzenesulfonyl chloride; Benzenesulfonyl chloride, 4-bromo-2,6-dimethyl-; (4-Bromo-2,6-dimethylphenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,6-Dimethylbenzene-1-Sulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and process chemistry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.