Description

3-Bromo-5-(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional aromatic sulfonyl chloride derivative. This compound serves as a critical synthetic intermediate, prized for its reactive sulfonyl chloride group and halogenated, fluorinated aromatic core, enabling precise molecular construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that leverage the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Research: Essential reagent in organic synthesis for introducing the benzenesulfonyl moiety into complex molecules for structure-activity relationship (SAR) studies.
• Dye and Pigment Industry: Intermediate in the production of specialized dyes and pigments where sulfone groups contribute to color fastness and solubility properties.

Basic Information

Product Name	3-Bromo-5-(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	351003-46-8
Molecular Formula	C7H3BrClF3O2S
Molecular Weight	323.51 g/mol
Synonyms	3-Bromo-5-(trifluoromethyl)benzene-1-sulfonyl chloride; 1-Bromo-3-(trifluoromethyl)-5-(chlorosulfonyl)benzene; 3-Bromo-alpha,alpha,α-trifluoro-m-toluenesulfonyl chloride; 3-Bromo-5-trifluoromethylbenzenesulfonyl chloride; m-Bromo-alpha,alpha,α-trifluorotoluenesulfonyl chloride; 3-Bromo-5-(trifluoromethyl)phenylsulfonyl chloride; Benzenesulfonyl chloride, 3-bromo-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-5-(Trifluoromethyl)Benzenesulfonyl Chloride adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.