Description

2-Bromo-4-Fluorobenzenesulfonyl Chloride is a versatile and highly reactive organosulfur compound primarily used as a key synthetic intermediate. Its value lies in the sulfonyl chloride functional group, which readily undergoes nucleophilic substitution reactions to form sulfonamides and sulfonate esters. This makes it an essential building block for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics with potential antibacterial, diuretic, or anticancer activity.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, where the sulfonyl moiety can contribute to biological activity and selectivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Derivatization: Employed in analytical chemistry and proteomics for labeling and modifying biomolecules to study structure and function.
• Ligand and Catalyst Development: Useful for creating novel sulfonated ligands for metal complexes used in catalytic processes.

Basic Information

Product Name	2-Bromo-4-Fluorobenzenesulfonyl Chloride
CAS No.	351003-45-7
Molecular Formula	C6H3BrClFO2S
Molecular Weight	273.51 g/mol
Synonyms	4-Fluoro-2-bromobenzenesulfonyl chloride; 2-Bromo-4-fluorobenzene-1-sulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-4-fluoro-; 1-Bromo-3-fluoro-4-(chlorosulfonyl)benzene; 4-Fluoro-2-bromophenylsulfonyl chloride; 2-Bromo-4-fluorophenylsulfonyl chloride; (2-Bromo-4-fluorophenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.