Description

2-Bromo-4,6-Difluorobenzenesulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its core value lies in its dual functionality as a sulfonylating agent and a halogenated aromatic scaffold, enabling the precise construction of complex molecules. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in the development of sulfonamide-based drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel sulfonamide drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Serves as a reactive handle for labeling proteins or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic & Industrial R&D: Employed in methodological research for new coupling reactions and heterocyclic compound formation.

Basic Information

Product Name	2-Bromo-4,6-Difluorobenzenesulfonyl Chloride
CAS No.	351003-42-4
Molecular Formula	C6H2BrClF2O2S
Molecular Weight	291.50 g/mol
Synonyms	2-Bromo-4,6-difluorobenzenesulfonyl chloride; 4,6-Difluoro-2-bromobenzenesulfonyl chloride; Benzenesulfonyl chloride, 2-bromo-4,6-difluoro-; 2-Bromo-4,6-difluorophenylsulfonyl chloride; (2-Bromo-4,6-difluorophenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4,6-Difluorobenzenesulfonyl Chloride is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.