Description

3-Cyano-4-Fluorobenzenesulfonyl Chloride is a high-purity, multi-functional chemical intermediate essential for advanced synthesis. This compound is valued for its reactive sulfonyl chloride and electron-withdrawing cyano and fluoro substituents, which enable precise molecular construction. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the development of modern herbicides and fungicides, leveraging its bioisosteric properties for enhanced efficacy.
• Material Science: Serves as a precursor for functional polymers and dyes, where the sulfonyl chloride group facilitates polymerization or conjugation.
• Chemical Research: A versatile reagent in organic synthesis for introducing the 4-fluoro-3-cyanophenylsulfonyl moiety into complex molecules.
• Ligand and Catalyst Development: Employed in the design of specialized ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	3-Cyano-4-Fluorobenzenesulfonyl Chloride
CAS No.	351003-23-1
Molecular Formula	C7H3ClFNO2S
Molecular Weight	219.62 g/mol
Synonyms	4-Fluoro-3-cyanobenzenesulfonyl chloride; 4-Fluoro-3-cyanobenzene-1-sulfonyl chloride; 3-Cyano-4-fluorobenzene-1-sulfonyl chloride; 2-Fluoro-5-(chlorosulfonyl)benzonitrile; 5-(Chlorosulfonyl)-2-fluorobenzonitrile; Benzonitrile, 5-(chlorosulfonyl)-2-fluoro-; 351003-23-1
EINECS	Contact for details

Quality Control

Every batch of 3-Cyano-4-Fluorobenzenesulfonyl Chloride is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure product integrity and traceability for your regulatory needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.