Description

2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride is a high-value, multi-functional chemical intermediate prized for its unique reactivity. Its core value proposition lies in its ability to act as a versatile sulfonylation reagent, introducing the highly stable and electron-withdrawing benzenesulfonyl group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients, particularly in the development of advanced fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring sulfonamide or sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from fluorinated sulfonyl groups for enhanced activity and stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and advanced materials with specific surface properties.
• Organic Synthesis Reagent: A critical reagent in organic chemistry for introducing sulfonyl protecting groups or creating sulfonamide linkages in complex molecule construction.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride
CAS No.	351003-22-0
Molecular Formula	C8H3ClF6O2S
Molecular Weight	312.61 g/mol
Synonyms	2,5-Bis(trifluoromethyl)benzenesulfonyl chloride; 1,4-Bis(trifluoromethyl)benzene-2-sulfonyl chloride; 2,5-Di(trifluoromethyl)benzenesulfonyl chloride; α,α,α,α',α',α'-Hexafluoro-2,5-xylene-ω-sulfonyl chloride; 2,5-Bis(trifluoromethyl)phenylsulfonyl chloride; 2,5-BTFBSCl; 2,5-Bis(trifluoromethyl)benzenesulphonyl chloride
EINECS	Contact for details

Quality Control

Our 2,5-Bis(Trifluoromethyl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.