Description

2-Bromo-4-Fluorobenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, combining bromine, fluorine, and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with fluorine-containing bioactive motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Negishi, and Stille couplings to form biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with specific fluorinated properties.

Basic Information

Product Name	2-Bromo-4-Fluorobenzotrifluoride
CAS No.	351003-21-9
Molecular Formula	C7H3BrF4
Molecular Weight	243.00 g/mol
Synonyms	1-Bromo-2-fluoro-5-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluoro-p-fluorotoluene; 2-Bromo-4-fluorobenzyl trifluoride; 2-Bromo-4-fluoro-α,α,α-trifluorotoluene; 2-Fluoro-5-(trifluoromethyl)bromobenzene; Benzene, 1-bromo-2-fluoro-5-(trifluoromethyl)-; (2-Bromo-4-fluorophenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorobenzotrifluoride is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.