Description

2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-n-(4-Isopropylphenyl)Acetamide is a high-purity, specialized purine derivative designed for advanced research and development. This compound matters as a critical building block and intermediate in the synthesis of novel pharmaceutical agents, particularly those targeting adenosine receptors. It is essential for medicinal chemistry researchers and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new active pharmaceutical ingredients (APIs), especially for neurological and cardiovascular targets.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Adenosine Receptor Ligand Synthesis: Serves as an intermediate in the preparation of potent and selective adenosine receptor antagonists or agonists.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for candidate drugs under Good Manufacturing Practice (GMP) guidelines.
• Biochemical Research: Utilized in enzymatic studies and as a tool compound for probing purinergic signaling pathways.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-n-(4-Isopropylphenyl)Acetamide
CAS No.	349085-38-7
Molecular Formula	C18H21N5O3
Molecular Weight	355.39 g/mol
Synonyms	N-(4-Isopropylphenyl)-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetamide; 7-[2-[(4-Isopropylphenyl)amino]-2-oxoethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 1,3-Dimethyl-7-[2-oxo-2-(4-propan-2-ylanilino)ethyl]purine-2,6-dione; A2A Adenosine Receptor Antagonist Intermediate; SCH 58261 Intermediate; Purine Acetamide Derivative
EINECS	Contact for details

Quality Control

Our 2-(1,3-Dimethyl-2,6-Dioxo-1,2,3,6-Tetrahydro-7H-Purin-7-Yl)-n-(4-Isopropylphenyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure compliance with stringent industry standards for research chemicals. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.