Description

Sns-032 CAS NO 345627-92-1 is a potent and selective small molecule inhibitor targeting specific cyclin-dependent kinases (CDKs), primarily CDK2, CDK7, and CDK9. This compound is crucial for disrupting cell cycle progression and transcription in research applications, offering a valuable tool for studying oncology pathways and cellular proliferation mechanisms. It is primarily needed by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on cancer biology, drug discovery, and molecular signaling.

Application

• Biochemical Research: Used as a selective inhibitor to study the roles of CDK2, CDK7, and CDK9 in cell cycle regulation and transcriptional control.
• Oncology Drug Discovery: Serves as a key reference compound and pharmacological tool in high-throughput screening and lead optimization for developing novel anti-cancer therapeutics.
• Mechanistic Studies: Employed in vitro and in cellular assays to investigate apoptosis, checkpoint control, and the downstream effects of CDK inhibition.
• Academic Research: A standard reagent for universities and research institutes exploring cell biology, signal transduction, and the molecular basis of diseases.
• Preclinical Development: Utilized in animal model studies to evaluate the efficacy and pharmacokinetics of CDK-targeting strategies.

Basic Information

Product Name	Sns-032
CAS No.	345627-92-1
Molecular Formula	C₂₁H₂₀N₈O₂S
Molecular Weight	448.50 g/mol
Synonyms	BMS-387032; SNS-032; N-(5-(((5-tert-Butyloxazol-2-yl)methyl)thio)thiazol-2-yl)piperidine-4-carboxamide; CDK Inhibitor SNS-032; BMS 387032; SNS 032; 5-[[(5-tert-Butyl-2-oxazolyl)methyl]thio]-2-thiazolamine, N-(4-piperidinylcarbonyl)-; AT7519 (structural analog, often referenced together)
EINECS	Contact for details

Quality Control

Our Sns-032 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation, NMR and MS for structural identity, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with research-grade standards and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.