Description

Sns-032 CAS NO 345627-80-7 is a high-purity, small molecule chemical compound widely recognized as a potent and selective inhibitor of cyclin-dependent kinases (CDKs). This compound is critical for researchers and developers in the life sciences sector, providing a valuable tool for modulating cell cycle progression and studying related biological pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, neurodegenerative diseases, and cell biology.

Application

• Pharmaceutical Research & Development: Serves as a key biochemical tool for investigating cell cycle regulation, apoptosis, and signal transduction pathways in disease models.
• Oncology Studies: Used in preclinical research to evaluate the therapeutic potential of CDK inhibition for various cancer types, including breast cancer, leukemia, and glioblastoma.
• Neurodegenerative Disease Research: Applied in studies exploring the role of cell cycle dysregulation in conditions like Alzheimer's and Parkinson's disease.
• Academic & Institutional Laboratories: Employed as a standard reagent for teaching and advanced research in molecular biology and pharmacology.
• Biomarker Discovery: Facilitates the identification and validation of novel cellular targets and biomarkers associated with CDK activity.
• High-Throughput Screening (HTS): Used as a reference compound in drug discovery campaigns to screen for new CDK inhibitors or assess compound libraries.

Basic Information

Product Name	Sns-032
CAS No.	345627-80-7
Molecular Formula	C₂₁H₂₀N₄O₂S
Molecular Weight	392.48 g/mol
Synonyms	BMS-387032; SNS-032; 6-[(2,6-Dichlorophenyl)methyl]-8-[(1R)-1-hydroxyethyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one; CDK Inhibitor SNS-032; BMS387032; SNS 032; SNS032; BAY 73-4506 (Note: This is a common mis-association; BAY 73-4506 is Regorafenib)
EINECS	Contact for details

Quality Control

Every batch of Sns-032 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay purity and impurity profiles. Our quality commitment aligns with standards expected for research-grade and pre-clinical materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.