Description

Pj-34 is a high-purity, small-molecule chemical compound widely recognized for its role as a potent and selective pharmacological inhibitor. This product is essential for research and development in life sciences, enabling precise biochemical pathway modulation. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in target validation and mechanistic studies.

Application

• Pharmacological Research: Used as a selective inhibitor of poly(ADP-ribose) polymerase (PARP) activity in experimental models.
• Neuroprotection Studies: Investigated for its potential neuroprotective effects in models of cerebral ischemia and neurodegenerative conditions.
• Cardiovascular Research: Applied in studies exploring myocardial infarction, ischemia-reperfusion injury, and related inflammatory pathways.
• Oncology Research: Employed in preclinical cancer research to study DNA repair mechanisms and cell death pathways.
• Biochemical Assay Development: Serves as a critical reference standard and tool compound in high-throughput screening and assay validation.
• Academic & Institutional R&D: A key reagent for universities and research institutes focusing on cell signaling, apoptosis, and oxidative stress.

Basic Information

Product Name	Pj-34
CAS No.	344458-19-1
Molecular Formula	C₁₃H₁₃N₃O₂
Molecular Weight	243.26 g/mol
Synonyms	PJ34; N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide; Phenanthridinone PJ34; PARP Inhibitor PJ34; 2-(Dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridin-2-yl)acetamide; PJ-34 HCl (Hydrochloride salt form)
EINECS	Contact for details

Quality Control

Our Pj-34 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.