Description

3-(2-Oxo-Pyrrolidin-1-Yl)Benzenesulfonyl Chloride CAS NO 344312-54-5 is a high-purity sulfonyl chloride derivative, a crucial building block in modern organic synthesis. Its primary value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the benzenesulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific sulfonamide functionalities.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling and modifying proteins or other biomolecules in research applications.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Academic & R&D: Serves as a critical reagent in university and institutional laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	3-(2-Oxo-Pyrrolidin-1-Yl)Benzenesulfonyl Chloride
CAS No.	344312-54-5
Molecular Formula	C10H10ClNO3S
Molecular Weight	259.71 g/mol
Synonyms	1-(3-Chlorosulfonylphenyl)-2-pyrrolidinone; 3-(2-Oxopyrrolidin-1-yl)benzenesulfonyl chloride; 3-(2-Oxo-1-pyrrolidinyl)benzenesulfonyl chloride; 1-(3-Chlorosulfonylphenyl)pyrrolidin-2-one; 3-(N-2-Oxopyrrolidinyl)benzenesulfonyl chloride; 3-(2-Oxopyrrolidino)benzenesulfonyl chloride; Benzenesulfonyl chloride, 3-(2-oxo-1-pyrrolidinyl)-
EINECS	Contact for details

Quality Control

Our 3-(2-Oxo-Pyrrolidin-1-Yl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.