Description

K+ Channel Inhibitor 1734 is a potent and selective small molecule compound designed for advanced research applications. This inhibitor plays a critical role in modulating potassium channel activity, enabling precise investigation into cellular signaling pathways and ion channel function. It is an essential tool for researchers and developers in the pharmaceutical and life sciences sectors, particularly those focused on cardiovascular, neurological, and metabolic disease research. The compound is supplied under stringent quality controls to ensure reliable and reproducible experimental results.

Application

• Primary research tool for studying the physiological and pathological roles of specific potassium (K+) channels.
• Preclinical pharmacological studies to evaluate potential therapeutic effects in models of cardiac arrhythmia.
• Investigation of neuronal excitability and synaptic transmission in neurological disorder research.
• Use in cellular assays for high-throughput screening (HTS) campaigns to identify novel drug candidates.
• Mechanistic studies in biochemistry and molecular biology to elucidate ion channel structure-function relationships.
• Development of diagnostic assays and research kits targeting potassium channel activity.

Basic Information

Product Name	K+ Channel Inhibitor 1734
CAS No.	343240-54-0
Molecular Formula	C₁₉H₂₀N₄O₃S
Molecular Weight	384.45 g/mol
Synonyms	BMS-191095; 4-[(3S)-3-[[(1S)-1-Phenylethyl]amino]-2-oxo-1-pyrrolidinyl]-2-(trifluoromethyl)benzonitrile; KATP Channel Inhibitor; Potassium Channel Blocker 1734; Pinacidil analog; SAR-109306
EINECS	Contact for details

Quality Control

Our K+ Channel Inhibitor 1734 is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and potency. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents. We adhere to high-purity standards suitable for research use, with typical purity levels exceeding 98% (by HPLC). Certificates are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Water Content (KF)	≤ 1.0% w/w
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.