Description

3-Methyl-5-Nitrophenylsulfonyl Chloride is a specialized aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, which enable it to act as a versatile electrophile for introducing the sulfonamide moiety, a key pharmacophore in many active molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and pesticides that incorporate sulfonylurea or sulfonamide structures.
• Dyestuff and Pigment Manufacturing: Serves as an intermediate for producing specialized azo dyes and organic pigments.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent for synthesizing specialty polymers with specific functional properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Ligand and Catalyst Design: Employed in the preparation of specialized ligands for metal catalysis or molecular recognition.

Basic Information

Product Name	3-Methyl-5-Nitrophenylsulfonyl Chloride
CAS No.	342422-23-5
Molecular Formula	C7H6ClNO4S
Molecular Weight	235.65 g/mol
Synonyms	3-Methyl-5-nitrobenzenesulfonyl chloride; 5-Nitro-m-toluenesulfonyl chloride; 3-Methyl-5-nitrobenzene-1-sulfonyl chloride; 2-Nitro-6-methylbenzenesulfonyl chloride (isomer reference); m-Toluenesulfonyl chloride, 5-nitro-; 342422-23-5; 3-Methyl-5-nitro phenyl sulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-5-Nitrophenylsulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.