Description

4-Methyl-Pyridine-2-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, enabling the efficient introduction of the 4-methylpyridine-2-sulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals. Its specific reactivity profile makes it indispensable for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the sulfonyl group can confer specific biological activity.
• Material Science Research: Employed in the creation of functionalized polymers, ligands for catalysis, and other specialty materials requiring sulfonamide linkages.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Fine Chemical Production: Serves as a precursor for other valuable sulfonamide and sulfonate derivatives used in various industrial chemical processes.

Basic Information

Product Name	4-Methyl-Pyridine-2-Sulfonyl Chloride
CAS No.	341008-95-5
Molecular Formula	C6H6ClNO2S
Molecular Weight	191.64 g/mol
Synonyms	2-Picoline-2-sulfonyl chloride; 4-Methylpyridine-2-sulfonyl chloride; 2-Methyl-4-sulfonylchloridopyridine; 4-Methyl-2-pyridinesulfonyl chloride; 2-Pyridinesulfonyl chloride, 4-methyl-; 4-Methyl-2-picolinesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-Pyridine-2-Sulfonyl Chloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to guarantee consistency, traceability, and reliability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.