Description

5-tert-Butyl-2,3-Dimethylbenzenesulfonyl Chloride (Saltdata: Free) is a high-purity, functionalized benzenesulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile sulfonylation reagent, enabling the introduction of the bulky, lipophilic 5-tert-butyl-2,3-dimethylphenylsulfonyl group into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in creating sulfonamide-based molecules with specific steric and electronic properties.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the sulfonyl chloride group is a crucial functional handle.
• Material Science Research: Employed in the synthesis of specialty polymers, dyes, and photoinitiators that require tailored sulfonated components.
• Chemical Biology & Proteomics: Acts as a reagent for modifying proteins, peptides, or other biomolecules to study function or create probes.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel sulfonated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, high-value sulfonyl derivatives.

Basic Information

Item	Details
Product Name	5-tert-Butyl-2,3-Dimethylbenzenesulfonyl Chloride (Saltdata: Free)
CAS No.	339370-16-0
Molecular Formula	C₁₂H₁₇ClO₂S
Molecular Weight	260.78 g/mol
Synonyms	5-tert-Butyl-2,3-dimethylbenzene-1-sulfonyl chloride; 2,3-Dimethyl-5-tert-butylbenzenesulfonyl chloride; 1-(tert-Butyl)-2,3-dimethyl-4-sulfonyl chloride benzene; (5-tert-Butyl-2,3-dimethylphenyl)sulfonyl chloride; 4-tert-Butyl-2,3-dimethylbenzenesulfonyl chloride (alternate numbering); Sulfonyl chloride derivative of tert-butylxylene
EINECS	Contact for details

Quality Control

Our production of 5-tert-Butyl-2,3-Dimethylbenzenesulfonyl Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.