Description

4-Benzyloxy-3-Methylbenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. This compound matters as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures essential for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science Research: Serves as a monomer or building block for developing organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organoboron reagents.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-Benzyloxy-3-Methylbenzeneboronic Acid
CAS No.	338454-30-1
Molecular Formula	C14H15BO3
Molecular Weight	242.08 g/mol
Synonyms	(4-(Benzyloxy)-3-methylphenyl)boronic acid; 3-Methyl-4-benzyloxybenzeneboronic acid; 4-(Benzyloxy)-3-methylbenzeneboronic acid; B-(4-Benzyloxy-3-methylphenyl)boronic acid; 338454-30-1; 4-Benzyloxy-3-methylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-3-Methylbenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.