Description

Cyclobutanesulfonyl Chloride CAS NO 338453-16-0 is a versatile and highly reactive sulfonyl chloride derivative featuring a strained cyclobutane ring. This compound serves as a critical building block in advanced organic synthesis, enabling the efficient introduction of the cyclobutanesulfonyl moiety. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures and developing active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for creating sulfonamide-based pharmacophores with potential therapeutic activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the cyclobutane ring confers unique biological properties.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal or mechanical characteristics.
• Chemical Biology Probe Development: Employed to create activity-based probes for studying enzyme function and protein labeling.
• Ligand & Catalyst Synthesis: Building block for constructing complex ligands used in asymmetric catalysis and organometallic chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke research projects and scale-up processes under cGMP or non-GMP conditions.

Basic Information

Product Name	Cyclobutanesulfonyl Chloride
CAS No.	338453-16-0
Molecular Formula	C4H7ClO2S
Molecular Weight	154.61 g/mol
Synonyms	Cyclobutanesulfonyl chloride; Cyclobutane-1-sulfonyl chloride; Cyclobutylsulfonyl chloride; 1-Cyclobutanesulfonyl chloride; Cyclobutanesulfonic acid chloride; 338453-16-0; Cyclobutanesulfonoyl chloride
EINECS	Contact for details

Quality Control

Our Cyclobutanesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to relevant ISO 9001 standards, and material is fully characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.