Description

4-(1,3-Oxazol-5-Yl)Benzenesulfonyl Chloride is a high-purity, heterocyclic sulfonyl chloride derivative serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of a functionalized aromatic sulfonyl group, which is essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides by acting as a sulfonating agent for bioactive scaffolds.
• Material Science: Building block for creating functional polymers and advanced materials with specific surface properties.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis: Serves as a versatile reagent for contract research organizations (CROs) and fine chemical suppliers specializing in bespoke molecular synthesis.

Basic Information

Product Name	4-(1,3-Oxazol-5-Yl)Benzenesulfonyl Chloride
CAS No.	337508-66-4
Molecular Formula	C9H6ClNO3S
Molecular Weight	243.67 g/mol
Synonyms	5-(4-Chlorosulfonylphenyl)oxazole; 4-(Oxazol-5-yl)benzenesulfonyl chloride; Benzenesulfonyl chloride, 4-(5-oxazolyl)-; 5-(4-Chlorosulfonylphenyl)-1,3-oxazole; 4-(1,3-Oxazol-5-yl)phenylsulfonyl chloride; 337508-66-4; 4-(Oxazol-5-Yl)Benzenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 4-(1,3-Oxazol-5-Yl)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.