Description

6A-Deoxy-6A-(4-Methyl-1-Piperazinyl)-β-Cyclodextrin is a chemically modified cyclodextrin derivative engineered to enhance the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients. This compound matters because it serves as a powerful and selective complexing agent, enabling the formulation of more effective and stable drug products. It is primarily needed by pharmaceutical R&D and manufacturing sectors for advanced drug delivery systems, as well as by analytical chemistry laboratories for chiral separation and molecular recognition studies.

Application

• Pharmaceutical Solubilization Agent: Key for enhancing the aqueous solubility and dissolution rate of hydrophobic drugs in oral and injectable formulations.
• Drug Delivery System Component: Used in the development of controlled-release and targeted delivery systems to improve drug stability and efficacy.
• Chiral Separation Media: Employed in chromatography (HPLC, CE) as a chiral selector for the resolution of enantiomeric compounds.
• Molecular Encapsulation: For masking unpleasant tastes or odors of APIs and protecting sensitive compounds from degradation.
• Chemical Synthesis Intermediate: Serves as a building block for synthesizing more complex functionalized cyclodextrins with tailored properties.
• Analytical Chemistry Reagent: Used in supramolecular chemistry research and sensor development for molecular recognition.

Basic Information

Product Name	6A-Deoxy-6A-(4-Methyl-1-Piperazinyl)-β-Cyclodextrin
CAS No.	337364-91-7
Molecular Formula	C49H84N7O34
Molecular Weight	~1299.22 g/mol
Synonyms	6A-Deoxy-6A-(4-methylpiperazino)-β-cyclodextrin; 6-Monodeoxy-6-mono(4-methyl-1-piperazinyl)-β-cyclodextrin; 6A-Mono(4-methylpiperazino)-6A-deoxy-β-cyclodextrin; Heptakis[6-deoxy-6-(4-methylpiperazinyl)]-β-cyclodextrin (incorrect for mono-substituted, but a common search variant); 6-O-(4-Methyl-1-piperazinyl)-6-deoxy-β-cyclodextrin; β-CD-6A-MP; 4-Methylpiperazinyl-β-cyclodextrin derivative; 6A-(N-Methylpiperazino)-6A-deoxy-β-cyclodextrin
EINECS	Contact for details

Quality Control

Our 6A-Deoxy-6A-(4-Methyl-1-Piperazinyl)-β-Cyclodextrin is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets precise specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details
Bacterial Endotoxins	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.